Open AI training and model evaluation roles that call for Chemistry expertise, gathered from 4 platforms. Part of Science & Research.
Pay figures cover the 24 open jobs that publish an hourly rate in USD. They are published rates, not a guarantee of income. Last checked on October 8, 2026.
A fully remote contract role where PhD-level biochemists create expert-level problems, author gold-standard solutions, and audit AI-generated biochemical reasoning to train and improve scientific AI models. Ideal for biochemists passionate about scientific rigor who want to shape the accuracy of next-generation AI without requiring prior AI experience.
This role involves helping train and refine AI models on biochemistry topics by designing test problems, writing ground-truth solutions, and evaluating AI-generated scientific reasoning. The position is ideal for PhD-level biochemists who want to apply their expertise to AI development while working flexibly on a remote, hourly contract basis.
This role involves annotating and evaluating chemistry content for AI model training. A PhD chemist will label complex chemistry questions, map conceptual relationships, review AI-generated answers, and develop datasets across multiple chemistry subfields to improve frontier AI models.
This role involves designing, solving, and evaluating advanced chemistry problems to train AI models. Masters and PhD-level chemists will leverage their domain expertise to create rigorous scientific content that enhances AI reasoning capabilities across organic, inorganic, physical, or computational chemistry.
Chemistry experts with PhD-level qualifications design rigorous chemistry problems and evaluate AI model responses for scientific accuracy and reasoning quality. This remote contract role involves assessing how AI systems understand complex chemistry concepts across multiple domains and providing detailed feedback to improve model performance.
Chemistry experts with a Master's degree help train AI systems to reason through complex scientific problems by designing chemistry problems, evaluating AI outputs, and providing feedback. This remote position suits chemistry specialists who want to apply their expertise to improve how AI models handle scientific content.
This role involves designing, solving, and evaluating complex chemistry problems to train AI models in scientific reasoning. Chemistry researchers with advanced degrees will apply their domain expertise to create rigorous problem sets and evaluate how AI systems understand chemistry concepts, working remotely on a flexible schedule.
This role involves designing, solving, and evaluating complex chemistry problems to train AI models. Chemistry experts with advanced degrees will apply their scientific knowledge to create rigorous problem sets and provide feedback on AI-generated scientific outputs, working remotely on a flexible schedule.
This role involves evaluating and improving AI systems that handle advanced chemistry problems by designing rigorous test cases and assessing the accuracy and reasoning quality of AI-generated solutions. Chemistry experts with Master's-level knowledge will work remotely to help AI systems better understand and reason through chemistry across multiple subdisciplines.
This role involves training advanced AI models to correctly understand environmental engineering concepts and identify flaws in their reasoning across water treatment, air quality, and hazardous waste remediation. You will design complex technical scenarios, write authoritative solutions, and critically evaluate AI outputs to improve how models think about environmental systems.
This role involves evaluating AI-generated chemical reasoning and responses to identify flawed mechanisms, unsafe procedures, and analytical errors. You will write prompts to test chemical knowledge, review AI outputs for errors, and provide correct expert-level answers with proper attention to safety and experimental conditions.
A drug discovery scientist will design realistic preclinical tasks and evaluate how well frontier AI models perform them, grading responses against professional standards. The role involves creating scenarios based on real workflows, running them through AI systems, and providing detailed feedback on whether the models correctly conduct SAR analysis, DMPK interpretation, screening triage, and other core discovery work.
Join a network of chemistry experts to evaluate and train the most advanced AI models. You will contribute to improving AI systems by assessing the quality of their chemical proposals, explaining your technical expertise, and flagging discrepancies between theory and practice.
Posted September 15, 2026
You will work on evaluating frontier AI models to test their ability to distinguish legitimate chemical requests from malicious uses. As a chemical defense researcher, you will write targeted questions, evaluate model responses against a defined policy framework, and document your judgments with rigorous technical justifications. This role requires deep expertise in chemical defense to draw the line between routine professional questions and those with high potential for misuse.
Posted September 14, 2026
You will contribute to evaluating AI models as a specialist chemist in energetic materials, by writing technical requests that test the model's ability to distinguish legitimate questions from dangerous requests. You will need to master the fine line between civilian applications and misuse to design realistic scenarios and evaluate the model's responses.
Posted September 14, 2026
You will write questions and scenarios to test an AI model's ability to correctly judge the potential for misuse of technical requests in chemistry, distinguishing legitimate questions from dangerous requests. This role requires practical expertise as a synthetic chemist or process engineer with experience scaling up reactions, and the ability to write clear technical justifications for non-specialists.
Posted September 14, 2026
You are a chemistry expert with practical experience in synthesis, analytical chemistry, or chemical safety. You participate in evaluating AI models by writing calibrated test prompts across three risk levels, then assessing model responses against an established safety framework. This role requires both advanced technical expertise and the ability to document your judgments in an accessible way.
Posted September 9, 2026
This role involves evaluating an AI model's responses to requests involving energetic materials and explosives, distinguishing between legitimate questions and dangerous requests. You will write progressively more complex test prompts, assess the model's responses against a defined safety policy, and provide written justification for your technical judgments. This role is intended for experts in materials chemistry specializing in propulsion and initiation systems, with solid practical experience in the field.
Posted September 9, 2026
This remote-style role asks PhD scientists who are fluent in both English and Indonesian to help make AI models safer on technical subjects. Contributors write expert prompts in Indonesian, then judge model answers for accuracy, helpfulness, and handling of sensitive material. No prior AI experience is needed because the workflow is taught on the job.
Posted September 4, 2026
This role involves designing realistic evaluation challenges for AI models applied to drug discovery. As an expert in chemistry and molecular biology, you will build complex research scenarios based on real and ambiguous data, where AI must demonstrate genuine reasoning capability rather than simple pattern association. You will be responsible for the entire process: challenge design, data corpus assembly, response evaluation, and iterative revision.
Posted August 31, 2026
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FAQ
25 Chemistry AI training jobs are open on SideHustler today. Listings are rechecked against the official postings: the latest check on this list was on October 8, 2026.
Among the 24 open roles that publish an hourly rate in USD, pay runs from $19 to $125 per hour, with a median of $70. These are the rates the platforms publish, not a guarantee of income or hours.
Mercor (12), Alignerr (10), DataAnnotation (2) and Terac (1). You apply on the platform itself, which handles screening, contracts and payment.
The most requested areas of expertise on these listings are AI Evaluation, Chemistry, Scientific Writing, Experimental Design, Data Annotation. Each listing states its own requirements.
Apply now opens the official posting on the platform, where you complete the application. You need no account on SideHustler. To see which roles fit your background first, add your resume and every open job is scored against your profile.
